Novel synthetic retinoids and separation of the pleiotropic retinoidal activitiesKAGECHIKA, Hiroyuki.Current medicinal chemistry. 2002, Vol 9, Num 5, pp 591-608, issn 0929-8673Article

Synthetic retinoids : Recent developments concerning structure and clinical utilityKAGECHIKA, Hiroyuki; SHUDO, Koichi.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 19, pp 5875-5883, issn 0022-2623, 9 p.Article

Utility of boron clusters for drug design. Relation between estrogen receptor binding affinity and hydrophobicity of phenols bearing various types of carboranyl groupsENDO, Yasuyuki; YAMAMOTO, Keisuke; KAGECHIKA, Hiroyuki et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 22, pp 4089-4092, issn 0960-894X, 4 p.Article

Sorafenib Induces Apoptosis Specifically in Cells Expressing BCR/ABL by inhibiting Its Kinase Activity to Activate the Intrinsic Mitochondrial PathwayKUROSU, Tetsuya; OHKI, Manabu; NAN WU et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 9, pp 3927-3936, issn 0008-5472, 10 p.Article

Diphenylamine-based retinoid antagonists: Regulation of RAR and RXR function depending on the N-substituentOHTA, Kiminori; KAWACHI, Emiko; FUKASAWA, Hiroshi et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 8, pp 2501-2507, issn 0968-0896, 7 p.Article

Activation of the Pl3 Kinase Pathway By Retinoic Acid Mediates Sodium/Iodide Symporter Induction and Iodide Transport in MCF-7 Breast Cancer CellsOHASHI, Emi; KOGAI, Takahiko; KAGECHIKA, Hiroyuki et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 8, pp 3443-3450, issn 0008-5472, 8 p.Article

Novel thyroid hormone receptor antagonists with an N-alkylated diphenylamine skeletonKOMATSU, Takuma; HIRANO, Tomoya; SONGKRAM, Chalermkiat et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 9, pp 3115-3126, issn 0968-0896, 12 p.Article

Novel retinoid X receptor (RXR) antagonists having a dicarba-closo-dodecaborane as a hydrophobic moietyOHTA, Kiminori; IIJIMA, Toru; KAWACHI, Emiko et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 23, pp 5913-5918, issn 0960-894X, 6 p.Article

Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structureFUJII, Shinya; OHTA, Kiminori; GOTO, Tokuhito et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 1, pp 344-350, issn 0968-0896, 7 p.Article

Efficient and diversity-oriented total synthesis of Riccardin C and application to develop novel macrolactam derivativesIWASHITA, Masazumi; FUJII, Shinya; ITO, Shigeru et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 33, issn 0040-4020, 5850, 6073-6082 [11 p.]Article

A novel melatonin derivative modulates sleep-wake cycle in ratsAKANMU, Moses A; SONGKRAM, Chalermkiat; KAGECHIKA, Hiroyuki et al.Neuroscience letters. 2004, Vol 364, Num 3, pp 199-202, issn 0304-3940, 4 p.Article

Docosahexaenoic acid reduces haloperidol-induced dyskinesias in mice: Involvement of Nur77 and retinoid receptorsETHIER, Isabelle; KAGECHIKA, Hiroyuki; SHUDO, Koichi et al.Biological psychiatry (1969). 2004, Vol 56, Num 7, pp 522-526, issn 0006-3223, 5 p.Article

Solvent-dependent conformational and fluorescence change of an N-phenylbenzohydroxamic acid derivative bearing two pyrene moietiesKANAI, Misae; HIRANO, Tomoya; AZUMAYA, Isao et al.Tetrahedron (Oxford. Print). 2012, Vol 68, Num 13, issn 0040-4020, 2738, 2778-2783 [7 p.]Article

Solvent-dependent conformational switching of N-phenylhydroxamic acid and its application in crystal engineeringYAMASAKI, Ryu; TANATANI, Aya; AZUMAYA, Isao et al.Crystal growth & design. 2006, Vol 6, Num 9, pp 2007-2010, issn 1528-7483, 4 p.Article

Determination of endogenous levels of retinoic acid isomers in type II diabetes mellitus patients. Possible correlation with Hba1c valuesYAMAKOSHI, Yuko; FUKASAWA, Hiroshi; YAMAUCHI, Toshimasa et al.Biological & pharmaceutical bulletin. 2002, Vol 25, Num 10, pp 1268-1271, issn 0918-6158, 4 p.Article

Cyclooxygenase inhibitors derived from thalidomideSUIZU, Mamiko; MUROYA, Yohei; KAKUTA, Hiroki et al.Chemical and pharmaceutical bulletin. 2003, Vol 51, Num 9, pp 1098-1102, issn 0009-2363, 5 p.Article

Novel retinoidal tropolone derivatives. Bioisosteric relationship of tropolone ring with benzoic acid moiety in retinoid structureEBISAWA, Masayuki; OHTA, Kiminori; KAWACHI, Emiko et al.Chemical and pharmaceutical bulletin. 2001, Vol 49, Num 4, pp 501-503, issn 0009-2363Article

Design and synthesis of cyclic urea compounds: a pharmacological study for retinoidal activityKURIHARA, Masaaki; ABU SHARA SHAMSUR ROUF; KANSUI, Hisao et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 16, pp 4131-4134, issn 0960-894X, 4 p.Article

α-glucosidase inhibitors with a 4,5,6,7-tetrachlorophthalimide skeleton pendanted with a cycloalkyl or dicarba-Closo-dodecaborane groupSOU, Sonei; TAKAHASHI, Hiroyasu; YAMASAKI, Ryu et al.Chemical and pharmaceutical bulletin. 2001, Vol 49, Num 6, pp 791-793, issn 0009-2363Article

Cyclic-tri(N-methyl-meta-benzamide)s: substituent effects on the bowl-shaped conformation in the crystal and solution statesKAKUTA, Hiroki; AZUMAYA, Isao; MASU, Hyuma et al.Tetrahedron (Oxford. Print). 2010, Vol 66, Num 42, issn 0040-4020, 8226, 8254-8260 [8 p.]Article

Synthesis and helical properties of aromatic multilayered oligoureasKUDO, Mayumi; KATAGIRI, Kosuke; AZUMAYA, Isao et al.Tetrahedron (Oxford. Print). 2012, Vol 68, Num 23, issn 0040-4020, 4333, 4455-4463 [10 p.]Article

Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release controlSATOH, Taku; HIGUCHI, Yuriko; KAWAKAMI, Shigeru et al.Journal of controlled release. 2009, Vol 136, Num 3, pp 187-195, issn 0168-3659, 9 p.Article

Effects of retinoic acids on the dendritic morphology of cultured hippocampal neuronsYING LIU; KAGECHIKA, Hiroyuki; ISHIKAWA, Junko et al.Journal of neurochemistry. 2008, Vol 106, Num 3, pp 1104-1116, issn 0022-3042, 13 p.Article

Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9MORI, Shuichi; IWASE, Kenta; IWANAMI, Naoko et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 23, pp 8158-8166, issn 0968-0896, 9 p.Article

Chiral Spherical Molecule Constructed from Aromatic Amides : Facile Synthesis and Highly Ordered Network Structure in the CrystalMASU, Hyuma; KATAGIRI, Kosuke; KATO, Takako et al.Journal of organic chemistry. 2008, Vol 73, Num 13, pp 5143-5146, issn 0022-3263, 4 p.Article